PPIs and the Prediction of Mutation-Induced Binding Free Energy Changes: What It All Means

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The study of protein-protein interactions (PPIs) and the prediction of mutation-induced binding free energy changes are of great importance

This paper is available on under CC 4.0 license. Arxiv Authors: Md Masud Rana, Department of Mathematics, University of Kentucky; Duc Duy Nguyen, Department of Mathematics, University of Kentucky & ducnguyen@uky.edu.

Brian J Bender, Alberto Cisneros III, Amanda M Duran, Jessica A Finn, Darwin Fu, Alyssa D Lokits, Benjamin K Mueller, Amandeep K Sangha, Marion F Sauer, Alexander M Sevy, et al. Protocols for molecular modeling with rosetta3 and rosettascripts. Biochemistry, 55:4748–4763, 2016. Kurt S Thorn and Andrew A Bogan. Asedb: a database of alanine mutations and their effects on the free energy of binding in protein interactions. Bioinformatics, 17:284–285, 2001. MD Shaji Kumar and M Michael Gromiha.

 

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