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Yes, lots can go wrong when taking a vacation. A study in the Netherlands found leisure sickness affected about 3 per cent of the sample after their return. The most frequently reported symptoms were headaches and migraines, fatigue, muscular pains, nausea and viral infections. Your first instinct may be to get through all those emails that have piled up, but Dr. Le Pertel advises beginning with essential and time-sensitive tasks and catching up on regular emails and updates later. She also urges that amid the complications of re-entry and the possible side effects of leisure sickness to still take time to reflect and savour the positive vacation experiences, as well as lessons and insights gained.